ARG58505
anti-Factor D antibody
anti-Factor D antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Factor D |
|---|---|
| 反应物种 | Ms, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Factor D |
| 抗原物种 | Rat |
| 抗原 | E. coli-derived Rat Factor D recombinant protein (Position: I26-A263). |
| 偶联标记 | Un-conjugated |
| 別名 | C3 convertase activator; PFD; Properdin factor D; DF; Complement factor D; ADIPSIN; EC 3.4.21.46; ADN; Adipsin |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | IHC-P: Antigen Retrieval: Heat mediated was performed in Citrate buffer (pH 6.0) for 20 min. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | CFD |
| 全名 | complement factor D (adipsin) |
| 背景介绍 | The protein encoded by this gene is a member of the trypsin family of peptidases. The encoded protein is a component of the alternative complement pathway best known for its role in humoral suppression of infectious agents. This protein is also a serine protease that is secreted by adipocytes into the bloodstream. Finally, the encoded protein has a high level of expression in fat, suggesting a role for adipose tissue in immune system biology. [provided by RefSeq, Jul 2008] |
| 生物功能 | Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway. [UniProt] |
| 细胞定位 | Secreted. [UniProt] |
| 预测分子量 | 27 kDa |
检测图片 (4) Click the Picture to Zoom In
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ARG58505 anti-Factor D antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Mouse lung tissue. Antigen Retrieval: Heat mediated was performed in Citrate buffer (pH 6.0, epitope retrieval solution) for 20 min. The tissue section was blocked with 10% goat serum. The tissue section was then stained with ARG58505 anti-Factor D antibody at 1 µg/ml dilution, overnight at 4°C.
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ARG58505 anti-Factor D antibody WB image
Western blot: 50 µg of samples under reducing conditions. RH35 and PC-12 cell lysates stained with ARG58505 anti-Factor D antibody at 0.5 µg/ml, overnight at 4°C.
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ARG58505 anti-Factor D antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Rat lung tissue. Antigen Retrieval: Heat mediated was performed in Citrate buffer (pH 6.0, epitope retrieval solution) for 20 min. The tissue section was blocked with 10% goat serum. The tissue section was then stained with ARG58505 anti-Factor D antibody at 1 µg/ml dilution, overnight at 4°C.
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ARG58505 anti-Factor D antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Rat small intestine tissue. Antigen Retrieval: Heat mediated was performed in Citrate buffer (pH 6.0, epitope retrieval solution) for 20 min. The tissue section was blocked with 10% goat serum. The tissue section was then stained with ARG58505 anti-Factor D antibody at 1 µg/ml dilution, overnight at 4°C.
