ARG41439
anti-Ferritin Heavy Chain antibody
anti-Ferritin Heavy Chain antibody for ICC/IF,Western blot and Human,Mouse,Rat
参考文献1
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Ferritin Heavy Chain |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Ferritin Heavy Chain |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide of Human Ferritin. |
| 偶联标记 | Un-conjugated |
| 別名 | Cell proliferation-inducing gene 15 protein; HFE5; FHC; PIG15; PLIF; Ferritin H subunit; FTH; Ferritin heavy chain; EC 1.16.3.1; FTHL6 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | Jurkat | ||||||
| 实际分子量 | ~ 20 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
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| 基因名称 | FTH1 |
| 全名 | ferritin, heavy polypeptide 1 |
| 背景介绍 | This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined. [provided by RefSeq, Jul 2008] |
| 生物功能 | Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity). [UniProt] |
| 预测分子量 | 21 kDa |
检测图片 (3) Click the Picture to Zoom In
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ARG41439 anti-Ferritin antibody ICC/IF image
Immunofluorescence: Jurkat cells stained with ARG41439 anti-Ferritin antibody.
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ARG41439 anti-Ferritin antibody WB image
Western blot: Jurkat cell lysate stained with ARG41439 anti-Ferritin antibody.
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ARG41439 anti-Ferritin antibody WB image
Western blot: GBC-SD cells stained with ARG41439 anti-Ferritin antibody.
From Desen Fan et al. Heliyon (2024), doi: 10.1016/j.heliyon.2024.e30260, Fig. 4. B.
文献引用
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WB / Human
