ARG67232
anti-Fibronectin antibody
anti-Fibronectin antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Drosophila,Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Fibronectin |
|---|---|
| 反应物种 | Hu, Ms, Rat, Drosophila |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Fibronectin |
| 偶联标记 | Un-conjugated |
| 別名 | FN1; Fibronectin 1; CIG; Cold-Insoluble Globulin; Lnc-ABCA12-8; GFND2; LETS; FINC; MSF; Migration-Stimulating Factor; Fibronectin; FN; Epididymis Secretory Sperm Binding Protein; SMDCF; ED-B; GFND; FNZ |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 100 mM Tris Glycine (pH 7.0), 0.025% ProClin 300 and 20% Glycerol. |
| 抗菌剂 | 0.025% ProClin 300 |
| 稳定剂 | 20% Glycerol |
| 浓度 | 1.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | FN1 |
| 全名 | Fibronectin 1 |
| 背景介绍 | This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. The encoded preproprotein is proteolytically processed to generate the mature protein. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants, at least one of which encodes an isoform that undergoes proteolytic processing. The full-length nature of some variants has not been determined. [provided by RefSeq, Jan 2016] |
| 生物功能 | Acts as a ligand for the LILRB4 receptor, inhibiting FCGR1A/CD64-mediated monocyte activation. [Uniprot] |
| 细胞定位 | Extracellular matrix, Secreted. [Uniprot] |
| 预测分子量 | 272 kDa |
| 翻译后修饰 | Disulfide bond; Glycoprotein; Isopeptide bond; Oxidation; Phosphoprotein; Pyrrolidone carboxylic acid; Sulfation. [Uniprot] |
检测图片 (3) Click the Picture to Zoom In
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ARG67232 anti-Fibronectin antibody IHC-P image
Immunohistochemistry: Breast Carcinoma stained with ARG67232 anti-Fibronectin antibody at 1:100 dilution.
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ARG67232 anti-Fibronectin antibody ICC/IF image
Immunofluorescence: PANC-1 stained with ARG67232 anti-Fibronectin antibody at 1:200 dilution.
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ARG67232 anti-Fibronectin antibody IHC-P image
Immunohistochemistry: Breast Carcinoma stained with ARG67232 anti-Fibronectin antibody at 1:100 dilution.
