ARG23602
anti-GDNF Receptor alpha 1 antibody
anti-GDNF Receptor alpha 1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes GDNF Receptor alpha 1 |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P, WB |
| 特异性 | GFR alpha 1 antibody is predicted to not cross-react with other members of the GFR alpha family of proteins. |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | GDNF Receptor alpha 1 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide around 14 aa (Center) of Human GDNF receptor alpha 1. |
| 偶联标记 | Un-conjugated |
| 別名 | GDNFR-alpha-1; GDNFRA; GFR-ALPHA-1; RET ligand 1; GFR-alpha-1; RET1L; GDNF receptor alpha-1; TRNR1; TGF-beta-related neurotrophic factor receptor 1; RETL1; GDNFR; GDNF family receptor alpha-1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | Human Brain |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | DEAE purified. |
| 缓冲液 | PBS and 0.02% Sodium azide |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | GFRA1 |
| 全名 | GDNF family receptor alpha 1 |
| 背景介绍 | Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Feb 2009] |
| 生物功能 | Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor (By similarity). [UniProt] |
| 预测分子量 | 51 kDa |
检测图片 (3) Click the Picture to Zoom In
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ARG23602 anti-GDNF Receptor alpha 1 antibody IHC-P image
Immunohistochemistry: Human brain tissue stained with ARG23602 anti-GDNF Receptor alpha 1 antibody at 1 µg/ml dilution.
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ARG23602 anti-GDNF Receptor alpha 1 antibody WB image
Western blot: Crude membrane fractions of Human brain, liver, kidney, and spleen lysates stained with ARG23602 anti-GDNF Receptor alpha 1 antibody at 1 µg/ml dilution.
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ARG23602 anti-GDNF Receptor alpha 1 antibody IHC-P image
Immunohistochemistry: Human brain tissue stained with ARG23602 anti-GDNF Receptor alpha 1 antibody at 2.5 µg/ml dilution.
