ARG64066
anti-GFAP antibody
anti-GFAP antibody for IHC-Frozen sections,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Controls and Markers antibody; Developmental Biology antibody; Neuroscience antibody; Signaling Transduction antibody; Astrocyte Marker antibody; Astrocyte Maturation Marker antibody; Neuroinflammation antibody; Brain Injury IHC Study antibody


概述
产品描述 | Goat Polyclonal antibody recognizes Glial Fibrillary Acidic Protein (GFAP) |
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反应物种 | Hu, Ms, Rat |
预测物种 | Dog |
应用 | IHC-Fr, IHC-P, WB |
特异性 | GFAP is thought to help to maintain astrocyte mechanical strength, as well as the shape of cells but its exact function remains poorly understood, despite the number of studies using it as a cell marker. |
宿主 | Goat |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | GFAP |
抗原物种 | Human |
抗原 | C-DGEVIKESKQEHKD |
偶联标记 | Un-conjugated |
別名 | Glial fibrillary acidic protein; ALXDRD; GFAP |
应用说明
应用建议 |
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应用说明 | WB: Recommend incubate at RT for 1h. IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Purified from goat serum by antigen affinity chromatography. |
缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA. |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 0.5% BSA |
浓度 | 0.5 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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全名 | glial fibrillary acidic protein |
背景介绍 | GFAP is one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008] |
生物功能 | GFAP is a class-III intermediate filament. It is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells. [UniProt] |
产品亮点 | Related Antibody Duos and Panels: ARG30007 Astrocyte Marker Antibody Duo (Host: Goat, Rabbit) Related products: GFAP antibodies; GFAP Duos / Panels; Anti-Goat IgG secondary antibodies; Related news: Astrocyte-to-neuron conversion for Parkinson's disease treatment |
研究领域 | Controls and Markers antibody; Developmental Biology antibody; Neuroscience antibody; Signaling Transduction antibody; Astrocyte Marker antibody; Astrocyte Maturation Marker antibody; Neuroinflammation antibody; Brain Injury IHC Study antibody |
预测分子量 | 50 kDa |
翻译后修饰 | Phosphorylated by PKN1. |
检测图片 (4) Click the Picture to Zoom In
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ARG64066 anti-GFAP antibody WB image
Western blot: 20 µg of Mouse brain and Rat brain lysates stained with ARG64066 anti-GFAP antibody at 1:5000 dilution.
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ARG64066 anti-GFAP antibody IHC-Fr image
Immunohistochemistry: PFA-perfused cryosection of Human hypothalamus tissue stained with ARG64066 anti-GFAP antibody at 0.01 µg/ml dilution.
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ARG64066 anti-GFAP antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human cortex tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG64066 anti-GFAP antibody at 5 µg/ml dilution followed by AP-staining.
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ARG64066 anti-GFAP antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human cerebellum tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG64066 anti-GFAP antibody at 2 µg/ml dilution, followed by HRP-staining.
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