ARG59586
anti-GIF / Gastric intrinsic factor antibody
anti-GIF / Gastric intrinsic factor antibody for ICC/IF,Western blot and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes GIF / Gastric intrinsic factor |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | GIF / Gastric intrinsic factor |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 20-300 of Human GIF (NP_005133.2). |
| 偶联标记 | Un-conjugated |
| 別名 | Gastric intrinsic factor; IFMH; TCN3; Intrinsic factor; INF; IF |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | Mouse pancreas |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | GIF |
| 全名 | gastric intrinsic factor (vitamin B synthesis) |
| 背景介绍 | This gene is a member of the cobalamin transport protein family. It encodes a glycoprotein secreted by parietal cells of the gastric mucosa and is required for adequate absorption of vitamin B12. Vitamin B12 is necessary for erythrocyte maturation and mutations in this gene may lead to congenital pernicious anemia. [provided by RefSeq, Jul 2008] |
| 生物功能 | Promotes absorption of the essential vitamin cobalamin (Cbl) in the ileum. After interaction with CUBN, the GIF-cobalamin complex is internalized via receptor-mediated endocytosis. [UniProt] |
| 细胞定位 | Secreted. [UniProt] |
| 预测分子量 | 45 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG59586 anti-GIF / Gastric intrinsic factor antibody ICC/IF image
Immunofluorescence: A549 cells stained with ARG59586 anti-GIF / Gastric intrinsic factor antibody.
