ARG44591
anti-GPR77 / C5L2 antibody [1D9-M12] (APC)
anti-GPR77 / C5L2 antibody [1D9-M12] (APC) for Flow cytometry and Human
概述
| 产品描述 | APC-conjugated Mouse Monoclonal antibody recognizes GPR77 / C5L2 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 1D9-M12 |
| 同位型 | IgG2a kappa |
| 靶点名称 | GPR77 / C5L2 |
| 抗原物种 | Human |
| 偶联标记 | APC |
| 別名 | C5AR2; Complement C5a Receptor 2; C5L2; Complement Component 5a Receptor 2; GPR77; C5a Anaphylatoxin Chemotactic Receptor 2; G Protein-Coupled Receptor 77; C5a Anaphylatoxin Chemotactic Receptor C5L2; G Protein-Coupled Receptor C5L2; G-Protein Coupled Receptor 77; GPF77 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified antibody is conjugated with activated allophycocyanin (APC), and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography. |
| 缓冲液 | PBS (pH 7.4) and 15 mM Sodium azide |
| 抗菌剂 | 15 mM Sodium azide |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9P296 Human C5a anaphylatoxin chemotactic receptor 2 |
|---|---|
| 基因名称 | C5AR2 |
| 全名 | complement component 5a receptor 2 |
| 背景介绍 | This gene encodes a G-protein coupled receptor 1 family member involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with intracellular G-proteins. It may instead modulate signal transduction through the beta-arrestin pathway, and may alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the pathogenesis of sepsis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012] |
| 生物功能 | Receptor for the chemotactic and inflammatory C3a, C4a and C5a anaphylatoxin peptides and also for their dearginated forms ASP/C3adesArg, C4adesArg and C5adesArg respectively. Couples weakly to G(i)-mediated signaling pathways. [UniProt] |
| 细胞定位 | Cell membrane, Membrane. [UniProt] |
| 预测分子量 | 36 kDa |
| 翻译后修饰 | Disulfide bond, Glycoprotein, Phosphoprotein. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG44591 anti-GPR77 / C5L2 antibody [1D9-M12] (APC) FACS image
Flow Cytometry: Human peripheral whole blood stained with ARG44591 anti-GPR77 / C5L2 antibody [1D9-M12] (APC) at 10 μl/ 100 μl dilution.
