ARG58731
anti-Galactosylceramidase antibody
anti-Galactosylceramidase antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Galactosylceramidase |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Galactosylceramidase |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 40-300 of Human Galactosylceramidase (NP_000144.2). |
| 偶联标记 | Un-conjugated |
| 別名 | Galactocerebroside beta-galactosidase; Galactosylceramidase; Galactocerebrosidase; Galactosylceramide beta-galactosidase; GALCERase; EC 3.2.1.46 |
应用说明
| 应用建议 |
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | 293T | ||||||||
| 实际分子量 | 77 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | GALC |
| 全名 | galactosylceramidase |
| 背景介绍 | This gene encodes a lysosomal protein which hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Mutations in this gene have been associated with Krabbe disease, also known as globoid cell leukodystrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] |
| 生物功能 | Hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Enzyme with very low activity responsible for the lysosomal catabolism of galactosylceramide, a major lipid in myelin, kidney and epithelial cells of small intestine and colon. [UniProt] |
| 细胞定位 | Lysosome. [UniProt] |
| 预测分子量 | 77 kDa |
检测图片 (2) Click the Picture to Zoom In
-
ARG58731 anti-Galactosylceramidase antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human gastric cancer stained with ARG58731 anti-Galactosylceramidase antibody at 1:100 dilution.
-
ARG58731 anti-Galactosylceramidase antibody WB image
Western blot: 25 µg of 293T cell lysate stained with ARG58731 anti-Galactosylceramidase antibody at 1:1000 dilution.
