ARG56797
anti-Galectin 3 antibody (Biotin)
anti-Galectin 3 antibody (Biotin) for ELISA,Western blot and Human
概述
产品描述 | Biotin-conjugated Rabbit Polyclonal antibody recognizes Galectin 3 |
---|---|
反应物种 | Hu |
应用 | ELISA, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | Galectin 3 |
抗原物种 | Human |
抗原 | E.coli derived Recombinant Human Galectin-3. (ADNFSLHDAL SGSGNPNPQG WPGAWGNQPA GAGGYPGASY PGAYPGQAPP GAYPGQAPPG AYHGAPGAYP GAPAPGVYPG PPSGPGAYPS SGQPSAPGAY PATGPYGAPA GPLIVPYNLP LPGGVVPRML ITILGTVKPN ANRIALDFQR GNDVAFHFNP RFNENNRRVI VCNTKLDNNW GREERQSVFP FESGKPFKIQ VLVEPDHFKV AVNDAHLLQY NHRVKKLNEI SKLGISGDID LTSASYTMI) |
偶联标记 | Biotin |
別名 | Laminin-binding protein; Gal-3; L-31; GALBP; Galactoside-binding protein; MAC2; GAL3; GALIG; Mac-2 antigen; CBP 35; Galectin-3; CBP35; Galactose-specific lectin 3; IgE-binding protein; L31; 35 kDa lectin; Carbohydrate-binding protein 35; Lectin L-29 |
应用说明
应用建议 |
|
||||||
---|---|---|---|---|---|---|---|
应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
---|---|
纯化 | Purified by affinity chromatography. |
缓冲液 | PBS (pH 7.2) |
浓度 | 1 mg/ml |
存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
---|---|
基因名称 | LGALS3 |
全名 | lectin, galactoside-binding, soluble, 3 |
背景介绍 | This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2014] |
生物功能 | Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. [UniProt] |
预测分子量 | 26 kDa |
检测图片 (4) Click the Picture to Zoom In
-
ARG56797 anti-Galectin 3 antibody (Biotin) WB image
Western blot: 250 - 0.24 ng of Human Galectin-3 stained with ARG56797 anti-Galectin 3 antibody (Biotin), under reducing conditions.
-
ARG56797 anti-Galectin 3 antibody (Biotin) standard curve image
Direct ELISA: ARG56797 anti-Galectin 3 antibody (Biotin) at 0.25 - 1.0 µg/ml results of a typical standard run with optical density.
-
ARG56797 anti-Galectin 3 antibody (Biotin) WB image
Western blot: 250 - 0.24 ng of Human Galectin-3 stained with ARG56797 anti-Galectin 3 antibody (Biotin), under non-reducing conditions.
-
ARG56797 anti-Galectin 3 antibody (Biotin) standard curve image
Sandwich ELISA: ARG56797 anti-Galectin 3 antibody (Biotin) as a detection antibody at 0.25 - 1.0 µg/ml combined with ARG56688 anti-Galectin 3 antibody as a capture antibody. Results of a typical standard run with optical density.