ARG44606
anti-Galectin 3 antibody [M3/38] (APC)
anti-Galectin 3 antibody [M3/38] (APC) for Flow cytometry and Human,Mouse
概述
| 产品描述 | APC-conjugated Rat Monoclonal antibody recognizes Galectin 3 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | FACS |
| 宿主 | Rat |
| 克隆 | Monoclonal |
| 克隆号 | M3/38 |
| 同位型 | IgG2a kappa |
| 靶点名称 | Galectin 3 |
| 抗原物种 | Human |
| 偶联标记 | APC |
| 別名 | LGALS3; Galectin 3; GALIG; Advanced Glycation End-Product Receptor 3; Lectin, Galactoside-Binding, Soluble, 3; Carbohydrate-Binding Protein 35; Galactose-Specific Lectin 3; Laminin-Binding Protein; IgE-Binding Protein; 35 KDa Lectin; Lectin L-29; Galectin-3 ; LGALS2; MAC-2; GALBP; MAC2; Epididymis Secretory Sperm Binding Protein; Galactoside-Binding Protein; MAC-2 Antigen; Mac-2 Antigen; CBP 35; CBP35; Gal-3; GAL3; L-31; L31 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified antibody is conjugated with activated allophycocyanin (APC), and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography. |
| 缓冲液 | PBS (pH 7.4) and 15 mM Sodium azide |
| 抗菌剂 | 15 mM Sodium azide |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | LGALS3 |
| 全名 | lectin, galactoside-binding, soluble, 3 |
| 背景介绍 | This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2014] |
| 生物功能 | In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. Together with TRIM16, coordinates the recognition of membrane damage with mobilization of the core autophagy regulators ATG16L1 and BECN1 in response to damaged endomembranes. [UniProt] |
| 细胞定位 | Cytoplasm, Nucleus, Secreted, Spliceosome. [UniProt] |
| 预测分子量 | 26 kDa |
| 翻译后修饰 | Acetylation, Disulfide bond, Phosphoprotein |
检测图片 (1) Click the Picture to Zoom In
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ARG44606 anti-Galectin 3 antibody [M3/38] (APC) FACS image
Flow Cytometry: SK-MEL-30 stained with ARG44606 anti-Galectin 3 antibody [M3/38] (APC) at 10 μl/ 100 μl dilution.
