ARG67067
anti-Glucagon antibody [SQab30338]
anti-Glucagon antibody [SQab30338] for IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Recombinant Rabbit Monoclonal antibody [SQab30338] recognizes Glucagon |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P |
| 宿主 | Rabbit |
| 克隆 | Monoclonal |
| 克隆号 | SQab30338 |
| 同位型 | IgG |
| 靶点名称 | Glucagon |
| 抗原物种 | Human |
| 抗原 | Recombinant protein fragment of Glucagon |
| 偶联标记 | Un-conjugated |
| Protein Full name | Glucagon |
| 別名 | GCG; Glucagon; GLP-1; GLP1; GLP2; GRPP; Glicentin-Related Polypeptide; Glucagon-Like Peptide 1; Glucagon-Like Peptide 2; Preproglucagon; Pro-Glucagon |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 40% Glycerol and 0.05% BSA |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | GCG |
| 全名 | glucagon |
| 背景介绍 | The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon. [provided by RefSeq, Jul 2008] |
| 生物功能 | Plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia. Plays an important role in initiating and maintaining hyperglycemic conditions in diabetes. [UniProt} |
| 细胞定位 | Secreted. [UniProt] |
| 产品亮点 | Related news: Studying obesity and appetite control by quantifying orexigenic and anorexigenic hormones; |
| 预测分子量 | 21 kDa |
| 翻译后修饰 | Amidation, Cleavage on pair of basic residues, Phosphoprotein. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG67067 anti-Glucagon antibody [SQab30338] IHC-P image
Immunohistochemistry: Human pancrease tissue stained with ARG67067 anti-Glucagon antibody [SQab30338] at 1:100 dilution.
