ARG20184
anti-HDAC7 antibody
anti-HDAC7 antibody for IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes HDAC7 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC-P, IP, WB |
| 特异性 | The antibody detects ~105 kDa HDAC7. The antibody does not recognize other members of the HDAC family. |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | HDAC7 |
| 抗原 | Synthetic peptide surrounding amino acid 921 of murine HDAC7 |
| 偶联标记 | Un-conjugated |
| 別名 | HD7; Histone deacetylase 7A; EC 3.5.1.98; Histone deacetylase 7; HD7a; HD7A; HDAC7A |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | Mouse small intestine tissue lysate can be use as a positive control. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity Purified Antibody |
| 缓冲液 | PBS (pH 7.2), 30% Glycerol, 0.5% BSA and 0.01% Thimerosal |
| 抗菌剂 | 0.01% Thimerosal |
| 稳定剂 | 30% Glycerol, 0.5% BSA |
| 浓度 | 0.2 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | HDAC7 |
| 全名 | histone deacetylase 7 |
| 背景介绍 | Human HDAC7 is composed of 912 amino acid residues. Although HDAC7 is localized mostly to the cell nucleus, it is also found in the cytoplasm, suggesting nucleo-cytoplasmic shuttling. The histone deacetylase activity of HDAC7 maps to a carboxy-terminal domain and is dependent on interaction with class I HDACs in the nucleus. HDAC7 catalyzes removal of acetyl-groups from acetyl-lysines of histones and promotes compaction of chromatin in these regions, leading to the inhibition of gene transcription. |
| 预测分子量 | 103 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG20184 anti-HDAC7 antibody WB image
Western Blot: Mouse small intestine tissue lysate stained with anti-HDAC7 antibody (ARG20184).
The antibody detects ~105 kDa HDAC7. Mouse small intestine tissue lysate can be use as a positive control. The antibody does not recognize other members of the HDAC family.
