概述

产品描述	Mouse Monoclonal antibody recognizes HERC4
反应物种	Hu, Rat
应用	WB
宿主	Mouse
克隆	Monoclonal
同位型	IgG1
靶点名称	HERC4
抗原物种	Human
抗原表位	IVLEPRKSDF FINKRVRDVG CGLRHTVFVL DDGTVYTCGC NDLGQLGHEK SRKKPEQVVA LDAQNIVAVS CGEAHTLALN DKGQVYAWGL DSDGQLGLVG SEECIRVPRN IKSLSDIQIV QVACGYYHSL ALSKASEVFC WGQNKYGQLG LGTDCKKQTS PQLLKSLLGI PFMQVAAGGA HSFVLTLSGA IFGWGRNKFG QLGLNDENDR YVPNLLKSLR SQKIVYICCG EDHTAALTKE
偶联标记	Un-conjugated
別名	HERC4; HECT And RLD Domain Containing E3 Ubiquitin Protein Ligase 4; KIAA1593; HECT Domain And RCC1-Like Domain-Containing Protein 4; Probable E3 Ubiquitin-Protein Ligase HERC4; HECT-Type E3 Ubiquitin Transferase HERC4; Hect Domain And RLD 4; DKFZP564G092; EC 2.3.2.26; EC 6.3.2

应用说明

应用建议	应用 推荐稀释比 WB 1:1000
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Protein A purification
缓冲液	PBS with 0.09% sodium azide
抗菌剂	0.09% sodium azide
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 26091 Human HERC4 GeneID: 309758 Rat HERC4 Swiss-port # Q5GLZ8 Human Probable E3 ubiquitin-protein ligase HERC4 Swiss-port # Q5PQN1 Rat Probable E3 ubiquitin-protein ligase HERC4
基因名称	HERC4
全名	HECT And RLD Domain Containing E3 Ubiquitin Protein Ligase 4
背景介绍	HERC4 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]).[supplied by OMIM, Mar 2008]
生物功能	Probable E3 ubiquitin-protein ligase involved in either protein trafficking or in the distribution of cellular structures. Required for spermatozoon maturation and fertility, and for the removal of the cytoplasmic droplet of the spermatozoon. E3 ubiquitin-protein ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer it to targeted substrates. [UniProt]
细胞定位	Cytoplasm. [UniProt]

检测图片 (1) Click the Picture to Zoom In