ARG45468
anti-HERPUD1 antibody
anti-HERPUD1 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes HERPUD1 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | HERPUD1 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein containing to human HERPUD1. |
| 偶联标记 | Un-conjugated |
| 別名 | HERPUD1; Homocysteine Inducible ER Protein With Ubiquitin Like Domain 1; HERP; KIAA0025; Mif1; SUP; Homocysteine-Inducible, Endoplasmic Reticulum Stress-Inducible, Ubiquitin-Like Domain Member 1; Homocysteine-Responsive Endoplasmic Reticulum-Resident Ubiquitin-Like Domain Member 1 Protein; Methyl Methanesulfonate (MMF)-Inducible Fragment Protein 1; Homocysteine-Inducible Endoplasmic Reticulum Stress-Inducible Ubiquitin-Like Domain Member 1 Protein; MMS-Inducible; MIF1 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 实际分子量 | 56 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q15011 Human Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like doma Swiss-port # Q9JJK5 Mouse Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like doma |
|---|---|
| 基因名称 | HERPUD1 |
| 全名 | Homocysteine Inducible ER Protein With Ubiquitin Like Domain 1 |
| 背景介绍 | The accumulation of unfolded proteins in the endoplasmic reticulum (ER) triggers the ER stress response. This response includes the inhibition of translation to prevent further accumulation of unfolded proteins, the increased expression of proteins involved in polypeptide folding, known as the unfolded protein response (UPR), and the destruction of misfolded proteins by the ER-associated protein degradation (ERAD) system. This gene may play a role in both UPR and ERAD. Its expression is induced by UPR and it has an ER stress response element in its promoter region while the encoded protein has an N-terminal ubiquitin-like domain which may interact with the ERAD system. This protein has been shown to interact with presenilin proteins and to increase the level of amyloid-beta protein following its overexpression. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms. The full-length nature of all transcript variants has not been determined. [provided by RefSeq, Jan 2013] |
| 生物功能 | Component of the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. [UniProt] |
| 细胞定位 | Endoplasmic reticulum; Membrane. [UniProt] |
| 预测分子量 | 44 kDa |
| 翻译后修饰 | Acetylation; Phosphoprotein. [UniProt] |
检测图片 (5) Click the Picture to Zoom In
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ARG45468 anti-HERPUD1 antibody IHC-P image
Immunohistochemistry: Human breast cancer stained with ARG45468 anti-HERPUD1 antibody at 2 μg/ml dilution.
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ARG45468 anti-HERPUD1 antibody ICC/IF image
Immunofluorescence: A549 stained with ARG45468 anti-HERPUD1 antibody at 5 μg/ml dilution.
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ARG45468 anti-HERPUD1 antibody WB image
Western blot: PC-3 stained with ARG45468 anti-HERPUD1 antibody at 0.5 μg/ml dilution.
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ARG45468 anti-HERPUD1 antibody WB image
Western blot: Rat liver stained with ARG45468 anti-HERPUD1 antibody at 0.5 μg/ml dilution.
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ARG45468 anti-HERPUD1 antibody WB image
Western blot: Mouse liver stained with ARG45468 anti-HERPUD1 antibody at 0.5 μg/ml dilution.
