ARG21428
anti-IFN gamma antibody [B27] (FITC)
anti-IFN gamma antibody [B27] (FITC) for ELISA,ELISPOT,Flow cytometry,ICC/IF,IHC-Frozen sections,Neutralizing and Human,African green monkey,Chimpanzee,Macaque,Rhesus Monkey
概述
| 产品描述 | FITC-conjugated Mouse Monoclonal antibody [B27 ] recognizes IFN gamma |
|---|---|
| 反应物种 | Hu, AGMK, Chimp, Macaq, R. Mk |
| 应用 | ELISA, ELISPOT, FACS, ICC/IF, IHC-Fr, Neut |
| 特异性 | Human/Rhesus/Cynomolgus/Chimpanzee/Pigtail Macaque/African Green Monkey/Sooty Mangabey IFN-γ. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | B27 |
| 同位型 | IgG1, kappa |
| 靶点名称 | IFN gamma |
| 抗原物种 | Human |
| 抗原 | E. coli-expressed human IFN-γ |
| 偶联标记 | FITC |
| 別名 | IFN-gamma; Interferon gamma; Immune interferon; IFG; IFI |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 缓冲液 | PBS and 0.1% Sodium azide. |
| 抗菌剂 | 0.1% Sodium azide |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | IFNG |
| 全名 | interferon, gamma |
| 背景介绍 | This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of the both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial inflections. Mutations in this gene are associated with an increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases. [provided by RefSeq, Sep 2015] |
| 生物功能 | Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. [UniProt] |
| 产品亮点 | Related products: IFN gamma antibodies; IFN gamma ELISA Kits; IFN gamma Duos / Panels; IFN gamma recombinant proteins; Anti-Mouse IgG secondary antibodies; Related news: HMGB1 in inflammation Inflammatory Cytokines |
| 预测分子量 | 19 kDa |
| 翻译后修饰 | Proteolytic processing produces C-terminal heterogeneity, with proteins ending alternatively at Gly-150, Met-157 or Gly-161. |
检测图片 (1) Click the Picture to Zoom In
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ARG21428 anti-IFN gamma antibody [B27] (FITC) FACS image
Flow Cytometry: PMA and lonomycin-stimulated Human peripheral blood lymphocytes stained with ARG21428 anti-IFN gamma antibody [B27] (FITC) and anti-CD3 antibody [UCHT1] (PE).
