ARG10675
anti-IGFBP3 antibody
anti-IGFBP3 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes IGFBP3 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | IGFBP3 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to the sequence at a.a 214-252 (RREMEDTLNHLKFLNVLSPRGVHIPNCDKKGFYKKKQCR) around the C-terminus of human IGFBP3 protein. |
| 偶联标记 | Un-conjugated |
| 別名 | IBP3; BP-53; IGF-binding protein 3; IGFBP-3 |
应用说明
| 应用建议 |
|
||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | IHC-P: Antigen Retrieval: Boil tissue sections in 10 mM Citrate buffer (pH 6.0) for 20 min * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
||||||
| 阳性对照 | Rat heart, Rat brain, Rat liver, PC-12, U-87 MG, Mouse kidney, Mouse heart and Mouse brain | ||||||
| 实际分子量 | ~ 40 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 1X PBS, 0.025% Sodium azide and 2.7% BSA |
| 抗菌剂 | 0.027% Sodium azide |
| 稳定剂 | 2.7% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | IGFBP3 |
| 全名 | Insulin Like Growth Factor Binding Protein 3 |
| 背景介绍 | This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] |
| 预测分子量 | 32 kDa |
| 翻译后修饰 | Phosphorylated by FAM20C in the extracellular medium. |
检测图片 (3) Click the Picture to Zoom In
-
ARG10675 anti-IGFBP3 antibody IHC-P image
Immunohistochemistry: Human intestinal cancer (paraffin-embedded sections) stained with ARG10675 anti-IGFBP3 antibody
Human intestinal cancer
-
ARG10675 anti-IGFBP3 antibody WB image
Western blot: 1) rat kidney, 2) rat liver, 3) human SGC, 4) human 22RV1 lysates stained with ARG10675 anti-IGFBP3 antibody
1) rat kidney, 2) rat liver, 3) human SGC, 4) human 22RV1
-
ARG10675 anti-IGFBP3 antibody WB image
Western blot: Rat heart, Rat brain, Rat liver, PC-12, U-87 MG, Mouse kidney, Mouse heart and Mouse brain lysates stained with ARG10675 anti-IGFBP3 antibody.
