ARG66099
anti-IGFBP3 antibody (Biotin)
anti-IGFBP3 antibody (Biotin) for ELISA and Human
概述
| 产品描述 | Biotin-conjugated Rabbit Polyclonal antibody recognizes IGFBP3 |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | IGFBP3 |
| 抗原物种 | Human |
| 抗原 | E. coli derived recombinant Human IGFBP3. (GASSGGLGPV VRCEPCDARA LAQCAPPPAV CAELVREPGC GCCLTCALSE GQPCGIYTER CGSGLRCQPS PDEARPLQAL LDGRGLCVNA SAVSRLRAYL LPAPPAPGNA SESEEDRSAG EVESPSVSST HRVSDPKFHP LHSKIIIIKK GHAKDSQRYK VDYESQSTDT QNFSSESKRE TEYGPCRREM EDTLNHLKFL NVLSPRGVHI PNCDKKGFYK KKQCRPSKGR KRGFCWCVDK YGQPLPGYTT KGKEDVHCYS MQSK) |
| 偶联标记 | Biotin |
| 別名 | IBP-3; IBP3; Insulin-like growth factor-binding protein 3; IGFBP-3; IGF-binding protein 3; BP-53 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified by affinity chromatography. |
| 缓冲液 | PBS (pH 7.2) |
| 浓度 | 1 mg/ml |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P17936 Human Insulin-like growth factor-binding protein 3 |
|---|---|
| 基因名称 | IGFBP3 |
| 全名 | insulin-like growth factor binding protein 3 |
| 背景介绍 | This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] |
| 生物功能 | IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R. [UniProt] |
| 预测分子量 | 32 kDa |
| 翻译后修饰 | Phosphorylated by FAM20C in the extracellular medium. |
检测图片 (2) Click the Picture to Zoom In
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ARG66099 anti-IGFBP3 antibody (Biotin) standard curve image
Direct ELISA: ARG66099 anti-IGFBP3 antibody (Biotin) at 0.25 - 1.0 µg/ml results of a typical standard run with optical density reading at 405 - 650 nm.
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ARG66099 anti-IGFBP3 antibody (Biotin) standard curve image
Sandwich ELISA: ARG66099 anti-IGFBP3 antibody (Biotin) as a detection antibody at 0.25 - 1.0 µg/ml combined with ARG66098 anti-IGFBP3 antibody as a capture antibody. Results of a typical standard run with optical density reading at 405 - 650 nm.
