ARG40140
anti-IL11RA antibody
anti-IL11RA antibody for Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes IL11RA |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | IL11RA |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide between aa. 372-403 of Human IL11RA. |
| 偶联标记 | Un-conjugated |
| 別名 | CRSDA; IL-11 receptor subunit alpha; IL-11RA; IL-11R subunit alpha; Interleukin-11 receptor subunit alpha; IL-11R-alpha |
应用说明
| 应用建议 |
|
||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | Jurkat |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A and immunogen peptide. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide. |
| 抗菌剂 | 0.09% (W/V) Sodium azide. |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q14626 Human Interleukin-11 receptor subunit alpha |
|---|---|
| 基因名称 | IL11RA |
| 全名 | interleukin 11 receptor, alpha |
| 背景介绍 | Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. This gene encodes the IL-11 receptor, which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012] |
| 生物功能 | Receptor for interleukin-11. The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission. The IL11/IL11RA/IL6ST complex may be involved in the control of proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells. Essential for the normal development of craniofacial bones and teeth. Restricts suture fusion and tooth number. [UniProt] |
| 细胞定位 | Membrane; Single-pass type I membrane protein. [UniProt] |
| 预测分子量 | 45 kDa |
检测图片 (1) Click the Picture to Zoom In
-
ARG40140 anti-IL11RA antibody WB image
Western blot: 20 µg of Jurkat whole cell lysate stained with ARG40140 anti-IL11RA antibody at 1:2000 dilution.
