ARG21450
anti-IL13 antibody [JES10-5A2]
anti-IL13 antibody [JES10-5A2] for ELISA,ELISPOT,Flow cytometry,ICC/IF,IHC-Frozen sections,Neutralizing and Human
概述
| 产品描述 | Rat Monoclonal antibody [JES10-5A2 ] recognizes IL13 |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA, ELISPOT, FACS, ICC/IF, IHC-Fr, Neut |
| 特异性 | Human IL-13. |
| 宿主 | Rat |
| 克隆 | Monoclonal |
| 克隆号 | JES10-5A2 |
| 同位型 | IgG1, kappa |
| 靶点名称 | IL13 |
| 抗原物种 | Human |
| 抗原 | COS-expressed human IL-13 |
| 偶联标记 | Un-conjugated |
| 別名 | Interleukin-13; P600; IL-13 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 缓冲液 | BBS (pH 8.2) |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | IL13 |
| 全名 | interleukin 13 |
| 背景介绍 | This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq, Jul 2008] |
| 生物功能 | Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses. [UniProt] |
| 预测分子量 | 16 kDa |
