ARG43844
anti-IL2 antibody [35C3]
anti-IL2 antibody [35C3] for ELISA,Flow cytometry,Immunoprecipitation,Western blot and Human
概述
| 产品描述 | Mouse Monoclonal antibody recognizes IL2. |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA, FACS, IP, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 35C3 |
| 同位型 | IgG2b kappa |
| 靶点名称 | IL2 |
| 抗原物种 | Human |
| 抗原 | Human IL2 recombinant protein. |
| 偶联标记 | Un-conjugated |
| Protein Full name | Interleukin-2 |
| 別名 | IL2; Interleukin 2; IL-2; TCGF; T Cell Growth Factor; Interleukin-2; Aldesleukin; Involved In Regulation Of T-Cell Clonal Expansion; T-Cell Growth Factor; Lymphokine |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein-A affinity chromatography |
| 缓冲液 | PBS (pH 7.4) and 15 mM Sodium azide |
| 抗菌剂 | 15 mM Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | Aliquot and store in the dark at 4°C. Keep protected from prolonged exposure to light. Do not freeze. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | IL2 |
| 全名 | Interleukin 2 |
| 背景介绍 | This gene is a member of the interleukin 2 (IL2) cytokine subfamily which includes IL4, IL7, IL9, IL15, IL21, erythropoietin, and thrombopoietin. The protein encoded by this gene is a secreted cytokine produced by activated CD4+ and CD8+ T lymphocytes, that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine (IL2R) is a heterotrimeric protein complex whose gamma chain is also shared by IL4 and IL7. The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. [provided by RefSeq, Sep 2020] |
| 生物功能 | Plays a pivotal role in regulating the adaptive immune system by controlling the survival and proliferation of regulatory T-cells, which are required for the maintenance of immune tolerance. Moreover, participates in the differentiation and homeostasis of effector T-cell subsets, including Th1, Th2, Th17 as well as memory CD8-positive T-cells. |
| 细胞定位 | Secreted |
| 预测分子量 | 18 kDa |
| 翻译后修饰 | Disulfide bond; Glycoprotein |
检测图片 (1) Click the Picture to Zoom In
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ARG43844 anti-IL2 antibody [35C3] FACS image
Flow Cytometry: Human whole blood stained with ARG43844 anti-IL2 antibody [35C3] at 0.5 μg/ml.
