ARG56680
anti-IL21 antibody
anti-IL21 antibody for ELISA,Neutralizing,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes IL21 |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA, Neut, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | IL21 |
| 抗原物种 | Human |
| 抗原 | E.coli derived Recombinant Human IL-21. (MQDRHMIRMR QLIDIVDQLK NYVNDLVPEF LPAPEDVETN CEWSAFSCFQ KAQLKSANTG NNERIINVSI KKLKRKPPST NAGRRQKHRL TCPSCDSYEK KPPKEFLERF KSLLQKMIHQ HLSSRTHGSE DS) |
| 偶联标记 | Un-conjugated |
| 別名 | Za11; IL-21; CVID11; Interleukin-21 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS (pH 7.2) |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | IL21 |
| 全名 | interleukin 21 |
| 背景介绍 | This gene encodes a member of the common-gamma chain family of cytokines with immunoregulatory activity. The encoded protein plays a role in both the innate and adaptive immune responses by inducing the differentiation, proliferation and activity of multiple target cells including macrophages, natural killer cells, B cells and cytotoxic T cells. Dysregulation of this gene plays a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011] |
| 生物功能 | Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells (By similarity). May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells. During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation. [UniProt] |
| 预测分子量 | 19 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG56680 anti-IL21 antibody WB image
Western blot: 250 - 0.24 ng of Human IL-21 stained with ARG56680 anti-IL21 antibody, under reducing conditions.
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ARG56680 anti-IL21 antibody standard curve image
Sandwich ELISA: ARG56680 anti-IL21 antibody as a capture antibody at 0.5 - 2.0 µg/ml combined with ARG56790 anti-IL21 antibody (Biotin) as a detection antibody. Results of a typical standard run with optical density.
