ARG59430
anti-IL23 Receptor antibody
anti-IL23 Receptor antibody for Western blot and Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes IL23 Receptor |
|---|---|
| 反应物种 | Ms |
| 预测物种 | Rat |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | IL23 Receptor |
| 抗原物种 | Mouse |
| 抗原 | Recombinant protein corresponding to I25-D233 of Mouse IL23 Receptor. |
| 偶联标记 | Un-conjugated |
| 別名 | Interleukin-23 receptor; IL-23R; IL-23 receptor |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 5% BSA. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | IL23R |
| 全名 | interleukin 23 receptor |
| 背景介绍 | The protein encoded by this gene is a subunit of the receptor for IL23A/IL23. This protein pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner. [provided by RefSeq, Jul 2008] |
| 生物功能 | Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis. [UniProt] |
| 细胞定位 | Cell membrane; Single-pass type I membrane protein. [UniProt] |
| 预测分子量 | 72 kDa |
| 翻译后修饰 | Phosphorylated in response to IL23. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG59430 anti-IL23 Receptor antibody WB image
Western blot: 50 µg of samples under reducing conditions. Mouse brain, Mouse liver and Mouse kidney lysates stained with ARG59430 anti-IL23 Receptor antibody at 0.5 µg/ml, overnight at 4°C.
