ARG59748
anti-IL27RA / WSX1 antibody
anti-IL27RA / WSX1 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes IL27RA / WSX1 |
|---|---|
| 反应物种 | Hu |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | IL27RA / WSX1 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide within the last 50 amino acids of Human IL27RA. |
| 偶联标记 | Un-conjugated |
| 別名 | IL27R; CRL1; Cytokine receptor-like 1; zcytor1; IL-27R subunit alpha; TCCR; IL-27R-alpha; Interleukin-27 receptor subunit alpha; ZcytoR1; Type I T-cell cytokine receptor; IL-27 receptor subunit alpha; WSX1; IL-27RA; Cytokine receptor WSX-1 |
应用说明
| 应用建议 |
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | Human spleen |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS and 0.02% Sodium azide |
| 抗菌剂 | 0.02% Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q6UWB1 Human Interleukin-27 receptor subunit alpha |
|---|---|
| 基因名称 | IL27RA |
| 全名 | interleukin 27 receptor, alpha |
| 背景介绍 | In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells, which are critical for cell-mediated immunity, predominantly under the influence of IL12. Also, IL4 influences their differentiation into type 2 (Th2) cells, which are critical for most antibody responses. Mice deficient in these cytokines, their receptors, or associated transcription factors have impaired, but are not absent of, Th1 or Th2 immune responses. This gene encodes a protein which is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level, and is predicted to be a glycosylated transmembrane protein. [provided by RefSeq, Jul 2008] |
| 生物功能 | Receptor for IL27. Requires IL6ST/gp130 to mediate signal transduction in response to IL27. This signaling system acts through STAT3 and STAT1. Involved in the regulation of Th1-type immune responses. Also appears to be involved in innate defense mechanisms. [UniProt] |
| 细胞定位 | Membrane; Single-pass type I membrane protein. [UniProt] |
| 预测分子量 | 69 kDa |
检测图片 (3) Click the Picture to Zoom In
-
ARG59748 anti-IL27RA / WSX1 antibody ICC/IF image
Immunofluorescence: Human spleen cells stained with ARG59748 anti-IL27RA / WSX1 antibody at 20 µg/ml dilution.
-
ARG59748 anti-IL27RA / WSX1 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human spleen stained with ARG59748 anti-IL27RA / WSX1 antibody at 5 µg/ml dilution.
-
ARG59748 anti-IL27RA / WSX1 antibody WB image
Western blot: Human spleen lysate stained with ARG59748 anti-IL27RA / WSX1 antibody at 1 µg/ml dilution.
