ARG66426
anti-IL33R / ST2 antibody [SQab18128]
anti-IL33R / ST2 antibody [SQab18128] for ELISA,Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Mouse Monoclonal antibody [SQab18128] recognizes IL33R / ST2 |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA, FACS, ICC/IF, IHC-P, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | SQab18128 |
| 同位型 | IgG1, kappa |
| 靶点名称 | IL33R / ST2 |
| 抗原物种 | Human |
| 抗原 | Recombinant Human IL33R / ST2 protein. |
| 偶联标记 | Un-conjugated |
| 別名 | IL33R; DER4; ST2V; T1; Interleukin-1 receptor-like 1; FIT-1; ST2; ST2L; Protein ST2 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 纯化 | Affinity purification with immunogen. |
|---|---|
| 缓冲液 | PBS (pH 7.4) and 0.01% Thimerosal. |
| 抗菌剂 | 0.01% Thimerosal |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | IL1RL1 |
| 全名 | interleukin 1 receptor-like 1 |
| 背景介绍 | The protein encoded by this gene is a member of the interleukin 1 receptor family. Studies of the similar gene in mouse suggested that this receptor can be induced by proinflammatory stimuli, and may be involved in the function of helper T cells. This gene, interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2) and interleukin 1 receptor-like 2 (IL1RL2) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008] |
| 生物功能 | Receptor for interleukin-33 (IL-33), its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. Possibly involved in helper T-cell function. [UniProt] |
| 细胞定位 | Isoform C: Cell membrane. Isoform B: Secreted. Cell membrane; Single-pass type I membrane protein. [UniProt] |
| 预测分子量 | 63 kDa |
检测图片 (4) Click the Picture to Zoom In
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ARG66426 anti-IL33R / ST2 antibody [SQab18128] ICC/IF image
Immunofluorescence: HT29 cells were fixed in 4% PFA, permeabilized with PBS containing 0.1% Triton X-100. Cells were stained with ARG66426 anti-IL33R / ST2 antibody [SQab18128] (green) at 1:400 and cell nuclei were stained with Hoechst 33342 (blue).
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ARG66426 anti-IL33R / ST2 antibody [SQab18128] FACS image
Flow Cytometry: HT29 cells were stained with ARG66426 anti-IL33R / ST2 antibody [SQab18128] at 1 µg/ml (red) and without antibody control (black).
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ARG66426 anti-IL33R / ST2 antibody [SQab18128] WB image
Western blot: 50 µg of HT29 cell lysate were stained with ARG66426 anti-IL33R / ST2 antibody [SQab18128] at 1:2000 dilution.
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ARG66426 anti-IL33R / ST2 antibody [SQab18128] ELISA image
ELISA: Titration curve of ARG66426 anti-IL33R / ST2 antibody [SQab18128]. Red: ST2; Black: BSA (negative control).
