ARG21472
anti-IL6 antibody [MP5-20F3] (low endotoxin)
anti-IL6 antibody [MP5-20F3] (low endotoxin) for ELISA,ELISPOT,Flow cytometry,ICC/IF,IHC-Frozen sections,IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Neutralizing and Mouse
概述
| 产品描述 | Azide free and low endotoxin Rat Monoclonal antibody [MP5-20F3 ] recognizes IL6 |
|---|---|
| 反应物种 | Ms |
| 应用 | ELISA, ELISPOT, FACS, ICC/IF, IHC-Fr, IHC-P, IP, Neut |
| 特异性 | Mouse IL-6. |
| 宿主 | Rat |
| 克隆 | Monoclonal |
| 克隆号 | MP5-20F3 |
| 同位型 | IgG1, kappa |
| 靶点名称 | IL6 |
| 抗原物种 | Mouse |
| 抗原 | COS-expressed mouse IL-6 |
| 偶联标记 | Un-conjugated |
| 別名 | B-cell stimulatory factor 2; CDF; HSF; BSF-2; Interferon beta-2; IL-6; IFNB2; CTL differentiation factor; Interleukin-6; HGF; Hybridoma growth factor; BSF2; IFN-beta-2 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化说明 | Low endotoxin |
| 缓冲液 | PBS |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | IL6 |
| 全名 | interleukin 6 |
| 背景介绍 | This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. [provided by RefSeq, Jun 2011] |
| 生物功能 | Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation. [UniProt] |
| 产品亮点 | Related products: IL6 antibodies; IL6 ELISA Kits; IL6 recombinant proteins; Anti-Rat IgG secondary antibodies; Related news: HMGB1 in inflammation Inflammatory Cytokines |
| 预测分子量 | 24 kDa |
| 翻译后修饰 | N- and O-glycosylated. |
检测图片 (1) Click the Picture to Zoom In
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ARG21472 anti-IL6 antibody [MP5-20F3] (low endotoxin) standard curve image
ELISA: Mouse IL-6 detected by ARG21471 anti-IL6 antibody [MP5-20F3] as capture antibody ( ARG21472: low endotoxin version), and ARG21474 anti-IL6 antibody [MP5-32C11] (Biotin) as detection antibody, follow by incubation with streptavidin-HRP.
