ARG21444

anti-IL6 antibody [MQ2-13A5]

anti-IL6 antibody [MQ2-13A5] for ELISA,ELISPOT,Flow cytometry,Immunoprecipitation,Neutralizing,Lateral flow assay and Human,Rhesus Monkey

publication_link 参考文献2

概述

产品描述 Rat Monoclonal antibody [MQ2-13A5] recognizes IL6
反应物种 Hu, R. Mk
应用 ELISA, ELISPOT, FACS, IP, Neut, lfa
特异性 Human/Rhesus/Cynomolgus IL-6.
宿主 Rat
克隆 Monoclonal
克隆号 MQ2-13A5
同位型 IgG1, kappa
靶点名称 IL6
抗原物种 Human
抗原 COS-expressed human IL-6
偶联标记 Un-conjugated
別名 B-cell stimulatory factor 2; CDF; HSF; BSF-2; Interferon beta-2; IL-6; IFNB2; CTL differentiation factor; Interleukin-6; HGF; Hybridoma growth factor; BSF2; IFN-beta-2

应用说明

应用建议
应用 推荐稀释比
ELISA< 5 µg/ml
ELISPOTAssay-dependent
FACSAssay-dependent
IPAssay-dependent
NeutAssay-dependent
lfaAssay-dependent
应用说明 Lateral flow assay was tested by the publication PMID: 34692664
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
缓冲液 BBS (pH 8.2)
浓度 1 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 3569 Human IL6

Swiss-port # P05231 Human Interleukin-6

基因名称 IL6
全名 interleukin 6
背景介绍 This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. [provided by RefSeq, Jun 2011]
生物功能 Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation. [UniProt]
产品亮点 Related products:
IL6 antibodies; IL6 ELISA Kits; IL6 recombinant proteins; Anti-Rat IgG secondary antibodies;
Related news:
HMGB1 in inflammation
Inflammatory Cytokines
预测分子量 24 kDa
翻译后修饰 N- and O-glycosylated.

检测图片 (1) Click the Picture to Zoom In

  • ARG21444 anti-IL6 antibody [MQ2-13A5] standard curve image

    ELISA: Human IL-6 detected by ARG21444 anti-IL6 antibody [MQ2-13A5] as capture antibody ( ARG21445: Azide free version), and ARG21447 anti-IL6 antibody [MQ2-39C3] (Biotin) as detection antibody, follow by incubation with streptavidin-HRP.

文献引用

Interleukin-6 Test Strip Combined With a Spectrum-Based Optical Reader for Early Recognition of COVID-19 Patients With Risk of Respiratory Failure

Lateral flow assay / 

Yung-Chih Wang et al.
Front Bioeng Biotechnol.,  (2022)

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A Paper-Based IL-6 Test Strip Coupled With a Spectrum-Based Optical Reader for Differentiating Influenza Severity in Children

Lateral flow assay / Human

Sheng-Wen Lin et al.
Front Bioeng Biotechnol.,  (2021)

publication_link

 

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