ARG67218
anti-KDM5D / Jarid1D / SMCY antibody
anti-KDM5D / Jarid1D / SMCY antibody for Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes KDM5D / Jarid1D / SMCY |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 靶点名称 | KDM5D / Jarid1D / SMCY |
| 抗原物种 | Human |
| 抗原 | Recombinant protein corresponding to C-terminal region of human KDM5D / Jarid1D / SMCY. |
| 偶联标记 | Un-conjugated |
| 別名 | KDM5D; Lysine Demethylase 5D; KIAA0234; JARID1D; SMCY; HYA; HY; Jumonji, AT Rich Interactive Domain 1D (RBP2-Like); [Histone H3]-Trimethyl-L-Lysine(4) Demethylase 5D; Jumonji/ARID Domain-Containing Protein 1D; Lysine (K)-Specific Demethylase 5D; Lysine-Specific Demethylase 5D; Histocompatibility Y Antigen; Histone Demethylase JARID1D; Protein SmcY; H-Y; Epididymis Secretory Sperm Binding Protein; Selected Mouse CDNA On Y, Human Homolog Of; Jumonji, AT Rich Interactive Domain 1D; Smcy Homolog, Y-Linked (Mouse); SMC Homolog, Y Chromosome; Smcy Homolog, Y-Linked; EC 1.14.11.67; EC 1.14.11 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein A purified |
| 缓冲液 | PBS |
| 浓度 | 0.1 - 1.0 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | KDM5D |
| 全名 | Lysine Demethylase 5D |
| 背景介绍 | This gene encodes a protein containing zinc finger domains. A short peptide derived from this protein is a minor histocompatibility antigen which can lead to graft rejection of male donor cells in a female recipient. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009] |
| 生物功能 | Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. May play a role in spermatogenesis. Involved in transcriptional repression of diverse metastasis-associated genes; in this function seems to cooperate with ZMYND8. Suppresses prostate cancer cell invasion. Regulates androgen receptor (AR) transcriptional activity by demethylating H3K4me3 active transcription marks. |
| 细胞定位 | Nucleus. [UniProt] |
| 翻译后修饰 | Isopeptide bond; Phosphoprotein; Ubl conjugation. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG67218 anti-KDM5D / Jarid1D / SMCY antibody WB image
Western blot: KDM5D / Jarid1D / SMCY recombinant protein stained with ARG67218 anti-KDM5D / Jarid1D / SMCY antibody.
