ARG43536
anti-LC3B antibody
anti-LC3B antibody for ICC/IF,Immunoprecipitation,Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes LC3B. |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, IP, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | LC3B |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide derived from human LC3B |
| 偶联标记 | Un-conjugated |
| Protein Full name | Microtubule-associated proteins 1A/1B light chain 3B |
| 別名 | LC3B; ATG8F; MAP1LC3B-a; MAP1A/1BLC3 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.4), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | MAP1LC3B |
| 全名 | microtubule-associated protein 1 light chain 3 beta |
| 背景介绍 | The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component. [provided by RefSeq, Jul 2008] |
| 生物功能 | Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway. [UniProt] |
检测图片 (4) Click the Picture to Zoom In
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ARG43536 anti-LC3B antibody ICC/IF image
Immunofluorescence: HeLa stained with ARG43536 anti-LC3B antibody.
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ARG43536 anti-LC3B antibody WB image
Western blot: Human brain stained with ARG43536 anti-LC3B antibody.
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ARG43536 anti-LC3B antibody WB image
Western blot: C6 stained with ARG43536 anti-LC3B antibody.
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ARG43536 anti-LC3B antibody WB image
Western blot: RAW 264.7 stained with ARG43536 anti-LC3B antibody.
