ARG55602
anti-LEFTY2 antibody
anti-LEFTY2 antibody for Western blot and Human
Cancer antibody; Developmental Biology antibody; Signaling Transduction antibody
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes LEFTY2 |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | LEFTY2 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein of Human LEFTY2. |
| 偶联标记 | Un-conjugated |
| 別名 | TGFB4; Transforming growth factor beta-4; Protein lefty-2; EBAF; LEFTA; Left-right determination factor 2; Left-right determination factor A; TGF-beta-4; Protein lefty-A; Endometrial bleeding-associated factor; LEFTYA |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | HeLa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A and immunogen peptide. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide |
| 抗菌剂 | 0.09% (W/V) Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | LEFTY2 |
| 全名 | left-right determination factor 2 |
| 背景介绍 | This gene encodes a member of the TGF-beta family of proteins. The encoded protein is secreted and plays a role in left-right asymmetry determination of organ systems during development. The protein may also play a role in endometrial bleeding. Mutations in this gene have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of this gene in the endometrium. Alternative processing of this protein can yield three different products. This gene is closely linked to both a related family member and a related pseudogene. Alternate splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2010] |
| 生物功能 | Required for left-right (L-R) asymmetry determination of organ systems in mammals. May play a role in endometrial bleeding. [UniProt] |
| 研究领域 | Cancer antibody; Developmental Biology antibody; Signaling Transduction antibody |
| 预测分子量 | 41 kDa |
| 翻译后修饰 | The processing of the protein may also occur at the second R-X-X-R site located at AA 132-135. Processing appears to be regulated in a cell-type specific manner. |
检测图片 (1) Click the Picture to Zoom In
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ARG55602 anti-LEFTY2 antibody WB image
Western blot: 20 µg of HeLa whole cell lysate stained with ARG55602 anti-LEFTY2 antibody at 1:8000 dilution.
