概述

产品描述	Rabbit Polyclonal antibody recognizes LIAS.
反应物种	Hu
应用	WB
宿主	Rabbit
克隆	Polyclonal
同位型	IgG
靶点名称	LIAS
抗原物种	Human
抗原	Synthetic peptide of Human LIAS.
偶联标记	Un-conjugated
別名	LIAS; Lipoic Acid Synthetase; LAS; Lipoyl Synthase, Mitochondrial; Lipoate Synthase; Lipoic Acid Synthase

应用说明

应用建议	应用 推荐稀释比 WB 1 : 500 - 1:2000
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Affinity purified.
缓冲液	PBS, 0.02% Sodium azide and 50% Glycerol.
抗菌剂	0.02% Sodium azide
稳定剂	50% Glycerol
浓度	1 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 11019 Human LIAS Swiss-port # O43766 Human Lipoyl synthase, mitochondrial
基因名称	LIAS
全名	Lipoic Acid Synthetase
背景介绍	The protein encoded by this gene belongs to the biotin and lipoic acid synthetases family. Localized in the mitochondrion, this iron-sulfur enzyme catalyzes the final step in the de novo pathway for the biosynthesis of lipoic acid, a potent antioxidant. The deficient expression of this enzyme has been linked to conditions such as diabetes, atherosclerosis and neonatal-onset epilepsy. Alternative splicing occurs at this locus, and several transcript variants encoding distinct isoforms have been identified.
生物功能	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
细胞定位	Mitochondrion
预测分子量	42 kDa

检测图片 (1) Click the Picture to Zoom In