ARG41983
anti-LIPE / HSL phospho (Ser853) antibody
anti-LIPE / HSL phospho (Ser853) antibody for Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes LIPE / HSL phospho (Ser853) |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | LIPE / HSL |
| 抗原物种 | Human |
| 抗原 | Phosphospecific peptide around Ser853 of Human LIPE / HSL. |
| 偶联标记 | Un-conjugated |
| 別名 | EC 3.1.1.79; AOMS4; HSL; LHS; Hormone-sensitive lipase; FPLD6 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | Mouse muscle + AP | ||||
| 实际分子量 | ~ 85 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | LIPE |
| 全名 | lipase, hormone-sensitive |
| 背景介绍 | The protein encoded by this gene has a long and a short form, generated by use of alternative translational start codons. The long form is expressed in steroidogenic tissues such as testis, where it converts cholesteryl esters to free cholesterol for steroid hormone production. The short form is expressed in adipose tissue, among others, where it hydrolyzes stored triglycerides to free fatty acids. [provided by RefSeq, Jul 2008] |
| 生物功能 | In adipose tissue and heart, it primarily hydrolyzes stored triglycerides to free fatty acids, while in steroidogenic tissues, it principally converts cholesteryl esters to free cholesterol for steroid hormone production. [UniProt] |
| 细胞定位 | Cell membrane. Membrane, caveola. Cytoplasm, cytosol. Note=Found in the high-density caveolae. Translocates to the cytoplasm from the caveolae upon insulin stimulation. [UniProt] |
| 预测分子量 | 117 kDa |
| 翻译后修饰 | Phosphorylation by AMPK may block translocation to lipid droplets. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG41983 anti-LIPE / HSL phospho (Ser853) antibody WB image
Western blot: Mouse muscle treated with AP. Tissue lysates were stained with ARG41983 anti-LIPE / HSL phospho (Ser853) antibody.
