ARG45369
anti-LTBP1 antibody [5L38]
anti-LTBP1 antibody [5L38] for IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Mouse Monoclonal antibody [5L38] recognizes LTBP1 |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 5L38 |
| 同位型 | IgG1 |
| 靶点名称 | LTBP1 |
| 抗原物种 | Human |
| 抗原 | Recombinant Human LTBP1. |
| 偶联标记 | Un-conjugated |
| 別名 | LTBP1; Latent Transforming Growth Factor Beta Binding Protein 1; Transforming Growth Factor Beta-1-Binding Protein 1; TGF-Beta1-BP-1; Latent-Transforming Growth Factor Beta-Binding Protein 1; LTBP-1; ARCL2E |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein G chromatography |
| 缓冲液 | PBS |
| 浓度 | 0.2 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q14766 Human Latent-transforming growth factor beta-binding protein 1 |
|---|---|
| 基因名称 | LTBP1 |
| 全名 | Latent Transforming Growth Factor Beta Binding Protein 1 |
| 背景介绍 | The protein encoded by this gene belongs to the family of latent TGF-beta binding proteins (LTBPs). The secretion and activation of TGF-betas is regulated by their association with latency-associated proteins and with latent TGF-beta binding proteins. The product of this gene targets latent complexes of transforming growth factor beta to the extracellular matrix, where the latent cytokine is subsequently activated by several different mechanisms. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
| 生物功能 | Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space |
| 细胞定位 | Extracellular matrix; Secreted. [UniProt] |
| 预测分子量 | 187 kDa |
| 翻译后修饰 | Disulfide bond; Glycoprotein; Hydroxylation; Phosphoprotein. [UniProt] |
检测图片 (1) Click the Picture to Zoom In
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ARG45369 anti-LTBP1 antibody [5L38] IHC-P image
Immunohistochemistry: Human placental stained with ARG45369 anti-LTBP1 antibody [5L38].
