ARG42646
anti-LTBR / Lymphotoxin beta Receptor antibody
anti-LTBR / Lymphotoxin beta Receptor antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes LTBR / Lymphotoxin beta Receptor |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | LTBR / Lymphotoxin beta Receptor |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide corresponding to aa. 420-435 of Human LTBR / Lymphotoxin beta Receptor (ATPSNRGPRNQFITHD). |
| 偶联标记 | Un-conjugated |
| 別名 | TNF-RIII; LT-BETA-R; Tumor necrosis factor receptor superfamily member 3; TNF-R-III; TNFR-III; TNFR-RP; TNFR3; D12S370; Tumor necrosis factor C receptor; Tumor necrosis factor receptor 2-related protein; TNFCR; Tumor necrosis factor receptor type III; Lymphotoxin-beta receptor; TNFR2-RP; CD18; TNFRSF3 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | HeLa and A549 | ||||||
| 实际分子量 | ~ 58 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl, 0.05% Sodium azide, 0.05% Thimerosal and 5% BSA. |
| 抗菌剂 | 0.05% Sodium azide and 0.05% Thimerosal |
| 稳定剂 | 5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P36941 Human Tumor necrosis factor receptor superfamily member 3 |
|---|---|
| 基因名称 | LTBR |
| 全名 | lymphotoxin beta receptor (TNFR superfamily, member 3) |
| 背景介绍 | This gene encodes a member of the tumor necrosis factor receptor superfamily. The major ligands of this receptor include lymphotoxin alpha/beta and tumor necrosis factor ligand superfamily member 14. The encoded protein plays a role in signalling during the development of lymphoid and other organs, lipid metabolism, immune response, and programmed cell death. Activity of this receptor has also been linked to carcinogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Aug 2012] |
| 生物功能 | Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs. [UniProt] |
| 细胞定位 | Membrane; Single-pass type I membrane protein. [UniProt] |
| 预测分子量 | 47 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG42646 anti-LTBR / Lymphotoxin beta Receptor antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human intestinal cancer tissue stained with ARG42646 anti-LTBR / Lymphotoxin beta Receptor antibody.
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ARG42646 anti-LTBR / Lymphotoxin beta Receptor antibody WB image
Western blot: 40 µg of HeLa and A549 whole cell lysates stained with ARG42646 anti-LTBR / Lymphotoxin beta Receptor antibody at 0.5 µg/ml dilution.
