ARG56604
anti-Leptin antibody [G1_4B6.3]
anti-Leptin antibody [G1_4B6.3] for ELISA,Western blot and Human
概述
| 产品描述 | Mouse Monoclonal antibody [G1_4B6.3] recognizes Leptin |
|---|---|
| 反应物种 | Hu |
| 应用 | ELISA, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | G1_4B6.3 |
| 同位型 | IgG1, kappa |
| 靶点名称 | Leptin |
| 抗原物种 | Human |
| 抗原 | E.coli derived Recombinant Human Leptin. (MVPIQKVQDD TKTLIKTIVT RINDISHTQS VSSKQKVTGL DFIPGLHPIL TLSKMDQTLA VYQQILTSMP SRNVIQISND LENLRDLLHV LAFSKSCHLP WASGLETLDS LGGVLEASGY STEVVALSRL QGSLQDMLWQ LDLSPGC) |
| 偶联标记 | Un-conjugated |
| 別名 | Leptin; Obese protein; OB; LEPD; Obesity factor; OBS |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS (pH 7.2) |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | LEP |
| 全名 | leptin |
| 背景介绍 | This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development. [provided by RefSeq, Jul 2008] |
| 生物功能 | May function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass. [UniProt] |
| 预测分子量 | 19 kDa |
