ARG44168
anti-MARCHF2 antibody
anti-MARCHF2 antibody for ICC/IF,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes MARCHF2 |
|---|---|
| 反应物种 | Hu |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | MARCHF2 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein of Human MARCHF2 |
| 偶联标记 | Un-conjugated |
| Protein Full name | E3 ubiquitin-protein ligase MARCHF2 |
| 別名 | MARCHF2; Membrane Associated Ring-CH-Type Finger 2; MARCH-II; RNF172; HSPC240; MARCH2; Membrane-Associated Ring Finger (C3HC4) 2, E3 Ubiquitin Protein Ligase; RING-Type E3 Ubiquitin Transferase MARCHF2; Membrane-Associated RING Finger Protein 2; Membrane-Associated RING-CH Protein II; E3 Ubiquitin-Protein Ligase MARCHF2; RING Finger Protein 172; Membrane-Associated Ring Finger (C3HC4) 2; RING-Type E3 Ubiquitin Transferase MARCH2; E3 Ubiquitin-Protein Ligase MARCH2; Membrane Associated Ring Finger 2; EC 2.3.2.27; EC 6.3.2 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 5% BSA. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9P0N8 Human E3 ubiquitin-protein ligase MARCH2 |
|---|---|
| 基因名称 | MARCHF2 |
| 全名 | Membrane Associated Ring-Ch-Type Finger 2 |
| 背景介绍 | MARCH2 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH2 reduces surface accumulation of several glycoproteins and appears to regulate early endosome-to-trans-Golgi network (TGN) trafficking. |
| 生物功能 | E3 ubiquitin-protein ligase that may mediate ubiquitination of TFRC and CD86, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. |
| 细胞定位 | Cell membrane, Cytoplasm, Endoplasmic reticulum, Endosome, Golgi apparatus, Lysosome, Membrane |
| 预测分子量 | 27 kDa |
检测图片 (2) Click the Picture to Zoom In
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ARG44168 anti-MARCHF2 antibody ICC/IF image
Immunofluorescence: HeLa stained with ARG44168 anti-MARCHF2 antibody at 5 μg/mL dilution.
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ARG44168 anti-MARCHF2 antibody WB image
Western blot: HEL, PC-3 and 293T stained with ARG44168 anti-MARCHF2 antibody at 0.5 μg/mL dilution.
