ARG44569
anti-MED28 / EG1 antibody
anti-MED28 / EG1 antibody for Flow cytometry,Western blot and Human
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes MED28 / EG1 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | MED28 / EG1 |
| 抗原物种 | Human |
| 抗原 | Human MED28 / EG1 recombinant protein (aa. sequence: M1-T178). |
| 偶联标记 | Un-conjugated |
| 別名 | MED28; Mediator Complex Subunit 28; Magicin 2; EG1; Mediator Of RNA Polymerase II Transcription Subunit 28; Merlin And Grb2-Interacting Cytoskeletal Protein; Tumor Angiogenesis Marker EG-1; Endothelial-Derived Protein 1; DKFZP434N185; Mediator Of RNA Polymerase II Transcription, Subunit 28 Homolog (S. Cerevisiae); Mediator Of RNA Polymerase II Transcription, Subunit 28 Homolog; Endothelial-Derived Gene 1; 1500003D12Rik |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 抗菌剂 | 4% Trehalose |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9H204 Human Mediator of RNA polymerase II transcription subunit 28 |
|---|---|
| 基因名称 | MED28 |
| 全名 | Mediator Complex Subunit 28 |
| 背景介绍 | Predicted to enable actin binding activity. Predicted to act upstream of or within negative regulation of smooth muscle cell differentiation and stem cell population maintenance. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] |
| 生物功能 | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May be part of a complex containing NF2/merlin that participates in cellular signaling to the actin cytoskeleton downstream of tyrosine kinase signaling pathways. [Uniprot] |
| 细胞定位 | Cytoplasm, Membrane, Nucleus. [Uniprot] |
| 预测分子量 | 20 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG44569 anti-MED28 / EG1 antibody WB image
Western blot: K562 and HepG2 stained with ARG44569 anti-MED28 / EG1 antibody at 0.5 μg/mL dilution.
