ARG56879
anti-MICB antibody
anti-MICB antibody for Western blot and Human
参考文献1
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes MICB |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | MICB |
| 抗原物种 | Human |
| 抗原 | Recombinant protein of Human MICB. |
| 偶联标记 | Un-conjugated |
| 別名 | MHC class I polypeptide-related sequence B; MIC-B; PERB11.2 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | NCI-H460 |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q29980 Human MHC class I polypeptide-related sequence B |
|---|---|
| 基因名称 | MICB |
| 全名 | MHC class I polypeptide-related sequence B |
| 背景介绍 | This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules; however, it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] |
| 生物功能 | Seems to have no role in antigen presentation. Acts as a stress-induced self-antigen that is recognized by gamma delta T cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis. [UniProt] |
| 产品亮点 | Related products: MICB antibodies; MICB ELISA Kits; Anti-Rabbit IgG secondary antibodies; Related news: Time to fight cancer by NK cells |
| 预测分子量 | 43 kDa |
| 翻译后修饰 | Proteolytically cleaved and released from the cell surface of tumor cells. |
检测图片 (1) Click the Picture to Zoom In
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ARG56879 anti-MICB antibody WB image
Western blot: NCI-H460 cell lysate stained with ARG56879 anti-MICB antibody.
文献引用
High MICB expression as a biomarker for good prognosis of colorectal cancer.
IHC-P / Human
