概述

产品描述	Rabbit Polyclonal antibody recognizes MIF
反应物种	Hu, Ms, Rat
应用	FACS, IP, WB
宿主	Rabbit
克隆	Polyclonal
同位型	IgG
靶点名称	MIF
抗原物种	Human
抗原	Synthetic peptide derived from Human MIF.
偶联标记	Un-conjugated
別名	Phenylpyruvate tautomerase; L-dopachrome tautomerase; GLIF; L-dopachrome isomerase; MMIF; Macrophage migration inhibitory factor; MIF; GIF; EC 5.3.2.1; Glycosylation-inhibiting factor; EC 5.3.3.12

应用说明

应用建议	应用 推荐稀释比 FACS 1:50 IP 1:50 WB 1:500 - 1:2000
应用说明	* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
实际分子量	11 kDa

属性

形式	Liquid
纯化	Affinity purified.
缓冲液	PBS (pH 7.4), 0.02% Sodium azide and 50% Glycerol.
抗菌剂	0.02% Sodium azide
稳定剂	50% Glycerol
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 17319 Mouse MIF GeneID: 4282 Human MIF GeneID: 81683 Rat MIF Swiss-port # P14174 Human Macrophage migration inhibitory factor Swiss-port # P30904 Rat Macrophage migration inhibitory factor Swiss-port # P34884 Mouse Macrophage migration inhibitory factor More
基因名称	MIF
全名	macrophage migration inhibitory factor (glycosylation-inhibiting factor)
背景介绍	This gene encodes a lymphokine involved in cell-mediated immunity, immunoregulation, and inflammation. It plays a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids. This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane, which may indicate an additional role in integrin signaling pathways. [provided by RefSeq, Jul 2008]
生物功能	Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity. [UniProt]
细胞定位	Secreted. Cytoplasm. Note=Does not have a cleavable signal sequence and is secreted via a specialized, non-classical pathway. Secreted by macrophages upon stimulation by bacterial lipopolysaccharide (LPS), or by M.tuberculosis antigens. [UniProt]
预测分子量	12 kDa

检测图片 (1) Click the Picture to Zoom In