ARG66363

anti-MMP15 antibody

anti-MMP15 antibody for Western blot and Human,Mouse

概述

产品描述 Rabbit Polyclonal antibody recognizes MMP15
反应物种 Hu, Ms
应用 WB
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 MMP15
抗原物种 Human
抗原 Fusion protein of Human MMP15.
偶联标记 Un-conjugated
別名 MT-MMP 2; Membrane-type matrix metalloproteinase 2; SMCP-2; MT2MMP; EC 3.4.24.-; Membrane-type-2 matrix metalloproteinase; MT2-MMP; MTMMP2; Matrix metalloproteinase-15; MMP-15

应用说明

应用建议
应用 推荐稀释比
WB1:500 - 1:2000
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照 Mouse stomach, heart and liver tissue, HT-29 cells.

属性

形式 Liquid
纯化 Affinity purification with immunogen.
缓冲液 PBS (pH 7.4), 0.05% Sodium azide and 40% Glycerol.
抗菌剂 0.05% Sodium azide
稳定剂 40% Glycerol
浓度 0.6 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 17388 Mouse MMP15

GeneID: 4324 Human MMP15

Swiss-port # O54732 Mouse Matrix metalloproteinase-15

Swiss-port # P51511 Human Matrix metalloproteinase-15

基因名称 MMP15
全名 matrix metallopeptidase 15 (membrane-inserted)
背景介绍 Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. [provided by RefSeq, Jul 2008]
生物功能 Endopeptidase that degrades various components of the extracellular matrix. May activate progelatinase A. [UniProt]
预测分子量 76 kDa
翻译后修饰 The precursor is cleaved by a furin endopeptidase. [UniProt]

检测图片 (1) Click the Picture to Zoom In

  • ARG66363 anti-MMP15 antibody WB image

    Western blot: 40 µg of Mouse stomach, Mouse heart, Mouse liver and HT29 cell lysates stained with ARG66363 anti-MMP15 antibody at 1:200 dilution.