ARG44544
anti-MMP20 antibody
anti-MMP20 antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes MMP20 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | MMP20 |
| 抗原物种 | Human |
| 抗原 | Human MMP20 synthesized peptide |
| 偶联标记 | Un-conjugated |
| 別名 | MMP20; Matrix Metallopeptidase 20 ; Matrix Metalloproteinase 20 (Enamelysin); Matrix Metalloproteinase-20; Enamel Metalloproteinase; Enamelysin; MMP-20; EC 3.4.24.22; EC 3.4.24.35; EC 3.4.24.-; EC 3.4.24; AI2A2 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity Purified |
| 缓冲液 | PBS (pH 7.4), 0.05% Sodium azide and 40% Glycerol. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 40% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | MMP20 |
| 全名 | Matrix Metallopeptidase 20 |
| 背景介绍 | Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene degrades amelogenin, the major protein component of dental enamel matrix, and thus thought to play a role in tooth enamel formation. A mutation in this gene, which alters the normal splice pattern and results in premature termination of the encoded protein, has been associated with amelogenesis imperfecta. This gene is part of a cluster of MMP genes located on chromosome 11q22.3. |
| 生物功能 | Degrades amelogenin, the major protein component of the enamel matrix and two of the macromolecules characterizing the cartilage extracellular matrix: aggrecan and the cartilage oligomeric matrix protein (COMP). May play a central role in tooth enamel formation. Cleaves aggrecan at the '360-Asn-|-Phe-361' site. |
| 细胞定位 | Extracellular matrix, Secreted |
| 预测分子量 | 54 kDa |
| 翻译后修饰 | Autocatalytic cleavage, Disulfide bond, Zymogen |
检测图片 (2) Click the Picture to Zoom In
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ARG44544 anti-MMP20 antibody WB image
Western blot: 823 stained with ARG44544 anti-MMP20 antibody.
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ARG44544 anti-MMP20 antibody WB image
Western blot: Mouse brain stained with ARG44544 anti-MMP20 antibody.
