ARG65851

anti-MMP7 antibody

anti-MMP7 antibody for Western blot and Human

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概述

产品描述 Rabbit Polyclonal antibody recognizes MMP7
反应物种 Hu
预测物种 Mk
应用 WB
特异性 Recognizes endogenous levels of MMP7 protein.
宿主 Rabbit
克隆 Polyclonal
同位型 IgG
靶点名称 MMP7
抗原物种 Human
抗原 KLH-conjugated synthetic peptide around the C-terminus of Human MMP7.
偶联标记 Un-conjugated
別名 MMP-7; Uterine metalloproteinase; Matrix metalloproteinase-7; EC 3.4.24.23; Matrilysin; Matrin; Pump-1 protease; PUMP-1; MPSL1

应用说明

应用建议
应用 推荐稀释比
WB1:500 - 1:1000
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式 Liquid
纯化 Affinity purification with immunogen.
缓冲液 Liquid (pH 7.3), 0.42% Potassium phosphate, 0.87% NaCl, 0.01% Sodium azide and 30% Glycerol.
抗菌剂 0.01% Sodium azide
稳定剂 30% Glycerol
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 4316 Human MMP7

Swiss-port # P09237 Human Matrilysin

基因名称 MMP7
全名 matrix metallopeptidase 7
背景介绍 MMP7 is a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal hemopexin domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes on chromosome 11. This gene exhibits elevated expression levels in multiple human cancers. [provided by RefSeq, Jan 2016]
生物功能 MMP7 degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase. [UniProt]
预测分子量 30 kDa

检测图片 (1) Click the Picture to Zoom In

  • ARG65851 anti-MMP7 antibody WB image

    Western blot: 20 µg of HT29 cell lysates stained with ARG65851 anti-MMP7 antibody at 1:500 dilution.

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anti-MMP7 antibody

Application:WB

Sample:HT29

Sample Loading Amount:20 µg

Primary Antibody Dilution Factor:1:500

Primary Antibody Incubation Time:overnight

Primary Antibody Incubation Temperature:4 ºC