ARG40613
anti-MMP9 antibody
anti-MMP9 antibody for ICC/IF,IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
Brain Injury IHC Study antibody
参考文献1
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes MMP9 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | MMP9 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 538-707 of Human MMP9 (NP_004985.2). |
| 偶联标记 | Un-conjugated |
| 別名 | Matrix metalloproteinase-9; 92 kDa gelatinase; MMP-9; Gelatinase B; GELB; CLG4B; MANDP2; EC 3.4.24.35; 92 kDa type IV collagenase |
应用说明
| 应用建议 |
|
||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | B cells | ||||||||
| 实际分子量 | 82 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | MMP9 |
| 全名 | matrix metallopeptidase 9 |
| 背景介绍 | Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. [provided by RefSeq, Jul 2008] |
| 生物功能 | May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide. [UniProt] |
| 细胞定位 | Secreted, extracellular space, extracellular matrix. [UniProt] |
| 研究领域 | Brain Injury IHC Study antibody |
| 预测分子量 | 78 kDa |
| 翻译后修饰 | Processing of the precursor yields different active forms of 64, 67 and 82 kDa. Sequentially processing by MMP3 yields the 82 kDa matrix metalloproteinase-9. N- and O-glycosylated. [UniProt] |
检测图片 (2) Click the Picture to Zoom In
-
ARG40613 anti-MMP9 antibody WB image
Western blot: Mouse endothelial cells stained with ARG40613 anti-MMP9 antibody at 1:1000 dilution.
From Wei-Ting Chang et al. Aging (Albany NY). (2022), doi: 10.18632/aging.204122, Fig. 2.
-
ARG40613 anti-MMP9 antibody WB image
Western blot: 25 µg of B cells stained with ARG40613 anti-MMP9 antibody at 1:1000 dilution.
文献引用
Effects of STAT3 on aging-dependent neovascularization impairment following limb ischemia: from bedside to bench
WB / Mouse
