ARG66954

anti-MPO / Myeloperoxidase antibody

anti-MPO / Myeloperoxidase antibody for IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse

Inflammatory Cell Marker antibody; Neurophil Marker antibody
publication_link 参考文献1

概述

产品描述 Mouse Polyclonal antibody recognizes MPO / Myeloperoxidase
反应物种 Hu, Ms
应用 IHC-P
宿主 Mouse
克隆 Polyclonal
同位型 IgG
靶点名称 MPO / Myeloperoxidase
抗原物种 Human
抗原 Synthetic peptide of Human MPO / Myeloperoxidase.
偶联标记 Un-conjugated
Protein Full name Myeloperoxidase
別名 MPO; Myeloperoxidase; EC 1.11.2.2; 89 kDa myeloperoxidase; 84 kDa myeloperoxidase; Myeloperoxidase light chain; Myeloperoxidase heavy chain

应用说明

应用建议
应用 推荐稀释比
IHC-P1:50 - 1:200
应用说明 * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照 Human Lung

属性

形式 Liquid
纯化 Affinity purification with immunogen.
缓冲液 PBS, 0.02% Sodium azide, 50% Glycerol and 0.5% BSA.
抗菌剂 0.02% Sodium azide
稳定剂 50% Glycerol and 0.5% BSA
浓度 1 mg/ml
存放说明 For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项 For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接

GeneID: 17523 Mouse MPO

GeneID: 4353 Human MPO

Swiss-port # P05164 Human Myeloperoxidase

Swiss-port # P11247 Mouse Myeloperoxidase

基因名称 MPO
全名 myeloperoxidase
背景介绍 Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils. [provided by RefSeq, Nov 2014]
生物功能 Myeloperoxidase (MPO): Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity. [UniProt]
细胞定位 Lysosome. [UniProt]
产品亮点 Related Antibody Duos and Panels:
ARG30325 Inflammatory Cell Antibody Panel
Related products:
MPO antibodies; MPO ELISA Kits; MPO Duos / Panels; Anti-Mouse IgG secondary antibodies;
Related news:
Exploring Antiviral Immune Response
研究领域 Inflammatory Cell Marker antibody; Neurophil Marker antibody
预测分子量 60 kDa, 84 kDa, 89 kDa

检测图片 (1) Click the Picture to Zoom In

  • ARG66954 anti-MPO / Myeloperoxidase antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human lung tissue stained with ARG66954 anti-MPO / Myeloperoxidase antibody at 1:200 dilution (4°C, overnight).

文献引用

Trimebutine prevents corneal inflammation in a rat alkali burn model

IHC-P / Rat

Hitoshi Goto et al.
Sci Rep.,  (2024)

publication_link

 

hr_line