ARG66757
anti-MPO / Myeloperoxidase antibody [SQab20190]
anti-MPO / Myeloperoxidase antibody [SQab20190] for IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Recombinant Rabbit Monoclonal antibody [SQab20190] recognizes MPO / Myeloperoxidase |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P |
| 宿主 | Rabbit |
| 克隆 | Monoclonal |
| 克隆号 | SQab20190 |
| 同位型 | IgG |
| 靶点名称 | MPO / Myeloperoxidase |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide within aa. 150-250 of Human MPO / Myeloperoxidase. |
| 偶联标记 | Un-conjugated |
| 別名 | MPO; Myeloperoxidase; EC 1.11.2.2 |
应用说明
| 应用建议 |
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| 应用说明 | IHC-P: Antigen Retrieval: Heat mediation was performed in Tris/EDTA buffer (pH 9.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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| 阳性对照 | Liver tissue. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 40% Glycerol and 0.05% BSA |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | MPO |
| 全名 | myeloperoxidase |
| 背景介绍 | Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils. [provided by RefSeq, Nov 2014] |
| 生物功能 | Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity. [UniProt] |
| 细胞定位 | Lysosome. [UniProt] |
| 产品亮点 | Related products: MPO antibodies; MPO ELISA Kits; MPO Duos / Panels; Anti-Rabbit IgG secondary antibodies; Related news: Exploring Antiviral Immune Response |
| 预测分子量 | 84 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG66757 anti-MPO / Myeloperoxidase antibody [SQab20190] IHC-P image
Immunohistochemistry: Formalin/PFA-fixed and paraffin-embedded Human liver tissue. Antigen Retrieval: Heat mediation was performed in Tris/EDTA buffer (pH 9.0). The tissue section was stained with ARG66757 anti-MPO / Myeloperoxidase antibody [SQab20190] at 18°C - 25°C for 30 minutes.
