ARG57589
anti-MTNR1A antibody
anti-MTNR1A antibody for IHC-Formalin-fixed paraffin-embedded sections,Western blot and Human,Mouse,Rat
参考文献1
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes MTNR1A |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | MTNR1A |
| 抗原物种 | Human |
| 抗原 | Recombinant protein of Human MTNR1A. |
| 偶联标记 | Un-conjugated |
| 別名 | MEL-1A-R; Mel-1A-R; MT1; Melatonin receptor type 1A; Mel1a receptor |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | Mouse small intestine | ||||||
| 实际分子量 | 39 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide, 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | MTNR1A |
| 全名 | melatonin receptor 1A |
| 背景介绍 | This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin. [provided by RefSeq, Jul 2008] |
| 生物功能 | High affinity receptor for melatonin. Likely to mediates the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity. [UniProt] |
| 预测分子量 | 39 kDa |
检测图片 (3) Click the Picture to Zoom In
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ARG57589 anti-MTNR1A antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Mouse brain tissue stained with ARG57589 anti-MTNR1A antibody at 1:100 dilution.
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ARG57589 anti-MTNR1A antibody WB image
Western blot: 25 µg of Mouse small intestine lysate stained with ARG57589 anti-MTNR1A antibody at 1:3000 dilution.
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ARG57589 anti-MTNR1A antibody WB image
Western blot: Rat placental stained with ARG57589 anti-MTNR1A antibody at 1:1000 dilution, ARG65351 Goat anti-Rabbit IgG antibody (HRP) at 1:5000 dilution.
From Jinzhi Li et al. J Reprod Immunol. (2023), doi: 10.1016/j.jri.2023.104166, Fig. 2.B.
文献引用
Sleep deprivation during pregnancy leads to poor fetal outcomes in Sprague-Dawley rats
WB / Rat
