ARG56062
anti-MUC6 / Gastric Mucin antibody [CLH5]
anti-MUC6 / Gastric Mucin antibody [CLH5] for Flow cytometry,ICC/IF,IHC-Formalin-fixed paraffin-embedded sections and Human
概述
| 产品描述 | Mouse Monoclonal antibody [CLH5] recognizes MUC6 / Gastric Mucin |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, ICC/IF, IHC-P |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | CLH5 |
| 同位型 | IgG1, kappa |
| 靶点名称 | MUC6 / Gastric Mucin |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide of the gastric Mucin 6 tandem repeat sequence. |
| 偶联标记 | Un-conjugated |
| 別名 | Mucin-6; Gastric mucin-6; MUC-6 |
应用说明
| 应用建议 |
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| 应用说明 | Antigen retrieval for IHC-P: Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS (pH 7.4), 0.05% Sodium azide and 0.1 mg/ml BSA |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 0.1 mg/ml BSA |
| 浓度 | 0.2 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | MUC6 |
| 全名 | mucin 6, oligomeric mucus/gel-forming |
| 背景介绍 | The MUC6 gene encodes gastric mucin, a secreted glycoprotein that plays an essential role in epithelial cytoprotection from acid, proteases, pathogenic microorganisms, and mechanical trauma in the gastrointestinal tract (summary by Toribara et al., 1993 [PubMed 7680650]).[supplied by OMIM, Dec 2010] |
| 生物功能 | May provide a mechanism for modulation of the composition of the protective mucus layer related to acid secretion or the presence of bacteria and noxious agents in the lumen. Plays an important role in the cytoprotection of epithelial surfaces and are used as tumor markers in a variety of cancers. May play a role in epithelial organogenesis. [UniProt] |
| 细胞定位 | Cytoplasmic and secreted |
| 产品亮点 | Related products: Anti-Mouse IgG secondary antibodies; Related news: Wnt / beta-catenin signaling for gastric fundus specification More than a biomarker, CA19-9 is a therapeutic target of pancreatic cancer |
| 预测分子量 | 257 kDa |
| 翻译后修饰 | O-glycosylated. |
检测图片 (1) Click the Picture to Zoom In
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ARG56062 anti-MUC6 / Gastric Mucin antibody [CLH5] IHC-P image
Immunohistochemistry: Formalin-fixed, paraffin-embedded Human gastric carcinoma stained with ARG56062 anti-MUC6 / Gastric Mucin antibody [CLH5].
