ARG55970
anti-Mucin 5AC antibody [45M1]
anti-Mucin 5AC antibody [45M1] for IHC-Formalin-fixed paraffin-embedded sections and Human,Mouse,Rat
概述
| 产品描述 | Mouse Monoclonal antibody [45M1] recognizes Mucin 5AC |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 不反应物种 | Cow |
| 应用 | IHC-P |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 45M1 |
| 同位型 | IgG1, kappa |
| 靶点名称 | Mucin 5AC |
| 抗原物种 | Human |
| 抗原 | Mucin preparation from the fluid of an ovarian mucinous cyst belonging to an O Le(a-b) patient. |
| 偶联标记 | Un-conjugated |
| 別名 | leB; Major airway glycoprotein; Lewis B blood group antigen; Tracheobronchial mucin; mucin; Mucin-5AC; LeB; MUC5; TBM; Gastric mucin; MUC-5AC; Mucin-5 subtype AC, tracheobronchial |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | IHC-P: Antigen Retrieval: Boil tissue section in 10 mM Citrate buffer (pH 6.0) for 10-20 min, followed by cooling at RT for 20 min. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS (pH 7.4), 0.05% Sodium azide and 0.1 mg/ml BSA |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 0.1 mg/ml BSA |
| 浓度 | 0.2 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | MUC5AC |
| 全名 | mucin 5AC, oligomeric mucus/gel-forming |
| 生物功能 | Gel-forming glycoprotein of gastric and respiratoy tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microrganisms and particles that are subsequently removed by the mucocilary system. [UniProt] |
| 细胞定位 | Cytoplasmic |
| 产品亮点 | Related products: Mucin 5AC antibodies; Anti-Mouse IgG secondary antibodies; Related news: Wnt / beta-catenin signaling for gastric fundus specification More than a biomarker, CA19-9 is a therapeutic target of pancreatic cancer |
| 预测分子量 | 586 kDa |
| 翻译后修饰 | C-, O- and N-glycosylated. O-glycosylated on the Thr-/Ser-rich tandem repeats. C-mannosylation in the Cys-rich subdomains may be required for proper folding of these regions and for export from the endoplasmic reticulum during biosynthesis. Proteolytic cleavage in the C-terminal is initiated early in the secretory pathway and does not involve a serine protease. The extent of cleavage is increased in the acidic parts of the secretory pathway. Cleavage generates a reactive group which could link the protein to a primary amide. |
检测图片 (3) Click the Picture to Zoom In
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ARG55970 anti-Mucin 5AC antibody [45M1] IHC-P image
Immunohistochemistry: Human stomach stained with ARG55970 anti-Mucin 5AC antibody [45M1].
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ARG55970 anti-Mucin 5AC antibody [45M1] IHC-P image
Immunohistochemistry: Human gastric carcinoma stained with ARG55970 anti-Mucin 5AC antibody [45M1].
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ARG55970 anti-Mucin 5AC antibody [45M1] IHC-P image
Immunohistochemistry: Rat stomach stained with ARG55970 anti-Mucin 5AC antibody [45M1].
