ARG44712
anti-NDUFAF1 antibody
anti-NDUFAF1 antibody for IHC-Formalin-fixed paraffin-embedded sections,Immunoprecipitation,Western blot and Human
概述
| 产品描述 | Mouse Monoclonal antibody recognizes NDUFAF1 |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P, IP, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG1 |
| 靶点名称 | NDUFAF1 |
| 抗原物种 | Human |
| 偶联标记 | Un-conjugated |
| 別名 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1; Complex I intermediate-associated protein 30, mitochondrial; CGI-65; CGI65; CIA30 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein A purification |
| 缓冲液 | PBS with 0.09% sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # Q9Y375 Human Complex I intermediate-associated protein 30, mitochondrial |
|---|---|
| 基因名称 | NDUFAF1 |
| 全名 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 1 |
| 背景介绍 | This gene encodes a complex I assembly factor protein. Complex I (NADH-ubiquinone oxidoreductase) catalyzes the transfer of electrons from NADH to ubiquinone (coenzyme Q) in the first step of the mitochondrial respiratory chain, resulting in the translocation of protons across the inner mitochondrial membrane. The encoded protein is required for assembly of complex I, and mutations in this gene are a cause of mitochondrial complex I deficiency. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 19. |
| 生物功能 | Chaperone protein involved in the assembly of the mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). [UniProt] |
| 预测分子量 | 150 kDa |
| 翻译后修饰 | N-glycosylation enhances cell surface expression and lengthens receptor half-life by preventing degradation in the ER. |
检测图片 (3) Click the Picture to Zoom In
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ARG44712 anti-NDUFAF1 antibody IHC-P image
Immunohistochemistry: Human kidney stained with ARG44712 anti-NDUFAF1 antibody at 5 µg/mL dilution.
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ARG44712 anti-NDUFAF1 antibody WB image
Western blot: HepG2 stained with ARG44712 anti-NDUFAF1 antibody at 1 µg/mL dilution.
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ARG44712 anti-NDUFAF1 antibody IP image
Immunoprecipitation: HepG2 lysate immunoprecipitated with 2.5 µg of ARG44712 anti-NDUFAF1 antibody.
