ARG40141
anti-NDUFV1 antibody
anti-NDUFV1 antibody for Western blot and Human,Mouse
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes NDUFV1 |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | NDUFV1 |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide between aa. 194-226 of Human NDUFV1. |
| 偶联标记 | Un-conjugated |
| 別名 | CI51KD; UQOR1; EC 1.6.5.3; NADH-ubiquinone oxidoreductase 51 kDa subunit; Complex I-51kD; NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; EC 1.6.99.3; NADH dehydrogenase flavoprotein 1; CI-51K; CI-51kD |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | HepG2 |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A and immunogen peptide. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide. |
| 抗菌剂 | 0.09% (W/V) Sodium azide. |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 |
Swiss-port # P49821 Human NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial Swiss-port # Q91YT0 Mouse NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial |
|---|---|
| 基因名称 | NDUFV1 |
| 全名 | NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa |
| 背景介绍 | The mitochondrial respiratory chain provides energy to cells via oxidative phosphorylation and consists of four membrane-bound electron-transporting protein complexes (I-IV) and an ATP synthase (complex V). This gene encodes a 51 kDa subunit of the NADH:ubiquinone oxidoreductase complex I; a large complex with at least 45 nuclear and mitochondrial encoded subunits that liberates electrons from NADH and channels them to ubiquinone. This subunit carries the NADH-binding site as well as flavin mononucleotide (FMN)- and Fe-S-biding sites. Defects in complex I are a common cause of mitochondrial dysfunction; a syndrome that occurs in approximately 1 in 10,000 live births. Mitochondrial complex I deficiency is linked to myopathies, encephalomyopathies, and neurodegenerative disorders such as Parkinson's disease and Leigh syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Oct 2009] |
| 生物功能 | Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). [UniProt] |
| 细胞定位 | Mitochondrion inner membrane; Peripheral membrane protein; Matrix side. [UniProt] |
| 预测分子量 | 51 kDa |
检测图片 (1) Click the Picture to Zoom In
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ARG40141 anti-NDUFV1 antibody WB image
Western blot: 20 µg of HepG2 cell lysate stained with ARG40141 anti-NDUFV1 antibody at 1:2000 dilution.
