ARG44568
anti-NETO2 antibody
anti-NETO2 antibody for Western blot and Human,Mouse,Rat
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes NETO2 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | NETO2 |
| 抗原物种 | Human |
| 抗原 | Human NETO2 recombinant protein (aa. sequence: I23-F525). |
| 偶联标记 | Un-conjugated |
| 別名 | NETO2; Neuropilin And Tolloid Like 2; NEOT2; Brain-Specific Transmembrane Protein Containing 2 CUB And 1 LDL-Receptor Class A Domains Protein 2; Neuropilin (NRP) And Tolloid (TLL)-Like 2; Neuropilin And Tolloid-Like Protein 2; FLJ10430; BTCL2 |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | 0.2% Na2HPO4, 0.9% NaCl and 4% Trehalose. |
| 抗菌剂 | 4% Trehalose |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | NETO2 |
| 全名 | Neuropilin And Tolloid Like 2 |
| 背景介绍 | This gene encodes a predicted transmembrane protein containing two extracellular CUB domains followed by a low-density lipoprotein class A (LDLa) domain. A similar gene in rats encodes a protein that modulates glutamate signaling in the brain by regulating kainate receptor function. Expression of this gene may be a biomarker for proliferating infantile hemangiomas. A pseudogene of this gene is located on the long arm of chromosome 8. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011] |
| 生物功能 | Accessory subunit of neuronal kainate-sensitive glutamate receptors, GRIK2 and GRIK3. Increases kainate-receptor channel activity, slowing the decay kinetics of the receptors, without affecting their expression at the cell surface, and increasing the open probability of the receptor channels. Modulates the agonist sensitivity of kainate receptors. Slows the decay of kainate receptor-mediated excitatory postsynaptic currents (EPSCs), thus directly influencing synaptic transmission. [Uniprot] |
| 细胞定位 | Membrane. [Uniprot] |
| 预测分子量 | 59 kDa |
| 翻译后修饰 | Disulfide bond, Glycoprotein, Phosphoprotein. [Uniprot] |
检测图片 (3) Click the Picture to Zoom In
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ARG44568 anti-NETO2 antibody WB image
Western blot: SIHA and SH-SY5Y stained with ARG44568 anti-NETO2 antibody at 0.5 μg/mL dilution.
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ARG44568 anti-NETO2 antibody WB image
Western blot: Rat brain and C6 stained with ARG44568 anti-NETO2 antibody at 0.5 μg/mL dilution.
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ARG44568 anti-NETO2 antibody WB image
Western blot: Mouse brain and Neuro-2a stained with ARG44568 anti-NETO2 antibody at 0.5 μg/mL dilution.
